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. 2020 Aug 26;10(9):1671. doi: 10.3390/nano10091671

Figure 9.

Figure 9

Gold nanoparticle mediated delivery of Gemcitabine. (A) Gemcitabine-conjugated GNPs showed a significant increase in efficacy when treating mice, as measured through volume. (B) KI67, a marker for proliferation, also showed reduced proliferative cells when treated with the GNP complex compared to the free drug alone, signifying improved efficacy. Black = vehicle, Red = GNP, Blue = Gem and Purple = GNP-Gem. * and ** denote p < 0.05 and p < 0.01 compared to vehicle-treated group respectively. Reproduced with permission from [169]. Copyright Royal Society of Chemistry, 2017.