Table 1.
Participant characteristics after case-control matching, stratified among gallbladder diseases.
|
Gallstone and gallbladder polyp disease |
Gallstone disease |
Gallbladder polyp disease |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Case group (n = 77) | Control group (n = 77) | P | Case group (n = 858) | Control group (n = 858) | P | Case group (n = 2553) | Control group (n = 2553) | P | |
| Age, years (mean ± standard deviation) | 50.5 ± 9.6 | 50.1 ± 10.1 | 0.769 | 54.1 ± 12.6 | 54 ± 12.9 | 0.876 | 46.8 ± 11.9 | 46.7 ± 12.1 | 0.943 |
| Sex, female (%) | 25 (32.5) | 25 (32.5) | 1.000 | 373 (43.5) | 373 (43.5) | 1.000 | 842 (33.0) | 842 (33.0) | 1.000 |
| H. pylori infection | 30 (39.0) | 33 (42.9) | 0.623 | 398 (46.4) | 420 (49.0) | 0.288 | 1214 (47.6) | 1157 (45.3) | 0.110 |
| Hypertension | 19 (24.7) | 10 (13.0) | 0.064 | 269 (31.4) | 217 (25.3) | 0.005 | 570 (22.3) | 484 (19.0) | 0.003 |
| Diabetes | 2 (2.6) | 5 (6.5) | 0.246 | 55 (6.4) | 49 (5.7) | 0.544 | 74 (2.9) | 78 (3.1) | 0.742 |
| Body mass index (kg/m2) | 24.1 ± 2.9 | 22.8 ± 2.8 | <0.001 | 25 ± 3.2 | 23.3 ± 3.1 | <0.001 | 24.3 ± 3 | 22.2 ± 3.1 | <0.001 |
| Underweight | 1 (1.3) | 1 (1.3) | 1.000 | 13 (1.5) | 13 (1.5) | 1.000 | 59 (2.3) | 59 (2.3) | 1.000 |
| Normal weight | 38 (49.4) | 38 (49.4) | 331 (38.6) | 331 (38.6) | 1192 (46.7) | 1192 (46.7) | |||
| Overweight | 31 (40.3) | 31 (40.3) | 373 (43.5) | 373 (43.5) | 1038 (40.7) | 1038 (40.7) | |||
| Obesity | 7 (9.1) | 7 (9.1) | 141 (16.4) | 141 (16.4) | 264 (10.3) | 264 (10.3) | |||
| Total bilirubin (µmol/L) | 13.1 ± 4.0 | 14.4 ± 6.7 | 0.134 | 14.4 ± 6.3 | 14.4 ± 5.9 | 0.793 | 14.4 ± 5.9 | 14.5 ± 5.8 | 0.711 |
| Direct bilirubin (µmol/L) | 3.8 ± 1.2 | 4.3 ± 2.1 | 0.069 | 4.2 ± 2.0 | 4.2 ± 1.8 | 0.948 | 4.2 ± 1.7 | 4.3 ± 1.7 | 0.559 |
| Indirect bilirubin (µmol/L) | 9.3 ± 3.1 | 10.1 ± 5.0 | 0.211 | 10.2 ± 4.6 | 10.2 ± 4.4 | 0.743 | 10.2 ± 4.4 | 10.2 ± 4.3 | 0.791 |
| Total bile acid (µmol/L) | 4.9 ± 4.7 | 3.6 ± 2.4 | 0.130 | 4.9 ± 5.0 | 4.5 ± 3.3 | 0.214 | 4.7 ± 6.7 | 4.5 ± 4.1 | 0.410 |
| Alanine aminotransferase (U/L) | 25.3 ± 16.8 | 26.7 ± 36.5 | 0.760 | 26.7 ± 23.4 | 23.1 ± 19.3 | 0.001 | 25.1 ± 23.3 | 22.7 ± 17.6 | <0.001 |
| Aspartate aminotransferase (U/L) | 22.7 ± 7.9 | 24.2 ± 17.2 | 0.498 | 24.8 ± 13.1 | 24.1 ± 11.9 | 0.258 | 23.3 ± 14.1 | 23.1 ± 9.4 | 0.494 |
| Alkaline phosphatase (U/L) | 30.8 ± 24.0 | 35.1 ± 57.6 | 0.540 | 36.6 ± 34 | 31.8 ± 36.8 | 0.005 | 32.2 ± 31.6 | 30.9 ± 37 | 0.188 |
| Triglyceride (mmol/L) | 1.8 ± 1.0 | 1.8 ± 1.6 | 0.998 | 2.0 ± 1.7 | 1.7 ± 1.9 | 0.007 | 1.8 ± 1.7 | 1.6 ± 1.4 | <0.001 |
| Total cholesterol (mmol/L) | 5.1 ± 0.9 | 5.1 ± 1.1 | 0.998 | 5.1 ± 1.0 | 5.1 ± 1.0 | 0.383 | 5.0 ± 1.0 | 5.0 ± 0.9 | 0.642 |
| High-density lipoprotein (mmol/L) | 1.4 ± 0.3 | 1.4 ± 0.3 | 0.533 | 1.4 ± 0.3 | 1.5 ± 0.3 | <0.001 | 1.4 ± 0.3 | 1.5 ± 0.3 | <0.001 |
| Low-density lipoprotein (mmol/L) | 2.8 ± 0.7 | 2.7 ± 0.8 | 0.824 | 2.7 ± 0.7 | 2.6 ± 0.7 | 0.167 | 2.6 ± 0.7 | 2.6 ± 0.7 | 0.005 |
| Leukocyte count (*109/L) | 6.6 ± 1.5 | 6.4 ± 1.6 | 0.376 | 6.5 ± 2.1 | 6.1 ± 1.6 | <0.001 | 6.3 ± 1.6 | 6.2 ± 1.6 | 0.014 |
| Neutrophil granulocyte count (*109/L) | 3.9 ± 1.2 | 3.7 ± 1.3 | 0.289 | 3.8 ± 1.3 | 3.6 ± 1.2 | <0.001 | 3.7 ± 1.2 | 3.6 ± 1.2 | 0.015 |
| Platelet count (*109/L) | 242.5 ± 56.1 | 238.6 ± 51.6 | 0.649 | 232.5 ± 55.8 | 228.8 ± 54.7 | 0.174 | 237.3 ± 53.1 | 233.9 ± 51.9 | 0.022 |
| Hemoglobin (g/L) | 147.8 ± 17.8 | 146.6 ± 13.2 | 0.631 | 143.8 ± 15.2 | 142.5 ± 15.1 | 0.076 | 146.3 ± 15.5 | 145.4 ± 15.1 | 0.036 |
Data are shown as n (%), except where otherwise indicated