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. 2020 Sep 6;10(9):1758. doi: 10.3390/nano10091758

Table 1.

Parameters about the electrosprayed nanoparticles.

No Process Voltage (kV) Flow Rate (mL/h) Morphology/Structure a Drug Loading in the NPs (w/w%) b
Core Fluid Shell Fluid
E1 Single-fluid 16 1.0 Irregular/Monolithic 23.1%
E2 Modified coaxial 18 1.0 0.3 Round/Core-shell 22.1%

a The morphology and structure are experimental results. b The drug loading in the nanoparticles (NPs) (w/w%) is a theoretical value calculated according to the electrospraying conditions. Because electrospraying is essentially a physical drying process and tamoxifen citrate (TAM) has a boiling point of 140–144 °C without sublimation property, the drug encapsulation efficiency can be regarded as 100% [27,46].