Table 4.
Association between rs4149313 and susceptibility to T2DM.
| Genetic model | Patient group | Control group | OR (95% CI) | P | OR (95% CI)* | P* | ||
|---|---|---|---|---|---|---|---|---|
| GA vs GG | 455 (42%) | 584 (54%) | 462 (41%) | 563 (50%) | 0.949 (0.798–1.129) | 0.558 | 0.964 (0.728–1.149) | 0.632 |
| AA vs GG | 47 (4%) | 584 (54%) | 97 (9%) | 563 (50%) | 0.467 (0.326–0.670) | <0.001 | 0.471 (0.311–0.679) | <0.001 |
| A vs G | 549 (25%) | 1623 (75%) | 656 (29%) | 1588 (71%) | 0.819 (0.717–0.935) | 0.003 | 0.824 (0.705–0.941) | 0.008 |
| Dominant | 502 (46%) | 584 (54%) | 559 (50%) | 563 (50%) | 0.866 (0.733–1.023) | 0.091 | 0.878 (0.721–1.047) | 0.123 |
| Recessive | 47 (4%) | 1039 (96%) | 97 (9%) | 1025 (91%) | 0.478 (0.336–0.680) | <0.001 | 0.501 (0.321–0.699) | <0.001 |
T2DM, type 2 diabetes mellitus; OR, odds ratio; CI, confidence interval; BMI, body mass index; HbA1c, glycated hemoglobin.
*Represents the values after adjustment for age, sex, BMI, blood pressure, and HbA1c.