Skip to main content
. 2020 Oct 10;14(1):100879. doi: 10.1016/j.tranon.2020.100879

Fig. 1.

Fig. 1

Par-4-mediated induction of miR-200c expression in cancer cell lines. (A) Heatmap showing results of miRNA microarray analysis upon GFP/GFP-Par-4 transfection in Panc-1 cells. The dendrogram shows different expression levels of miRNAs among the samples. Orange indicates the highest expression of miRNA, while blue indicates the lowest expression. (B) The graph shows the fold increase in the expression level of miR-200c upon GFP/GFP-Par-4-overexpression in Panc-1 cells. (C) Western blot data of the basal protein levels of Par-4, E-cadherin, Cytokeratin-18, and Vimentin in HCT-116, Panc-1, and A549 cells. Beta-actin was used as a loading control. (D) The bar graph represents the relative protein expression levels of Par-4, E-cadherin, Cytokeratin-18, and Vimentin in HCT-116, Panc-1, and A549 cell lines. (E) The bar graph depicts the differential miR-200c expression levels in HCT-116, Panc-1, and A549, as monitored by qRT-PCR. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)