Table 1.

Clinical and pathological parameters of AM patients in Chinese (n = 280) and Caucasians (n = 62).

Parameter	Chinese (n = 280) (%)	Caucasian (n = 62) (%)	p value
Age at diagnosis (years)			0.25
Median (IQR)	60.5 (51–70)	64.5 (49.5–75.3)
Gender			0.80
Male	154 (55)	33 (53.2)
Female	126 (46)	29 (46.8)
Male to female ratio	1.22 : 1	1.13 : 1
Pathologic stage			<0.001
0/I	43 (15.3)	38 (61.2)
II	160 (57.1)	11 (17.7)
III	76 (27.2)	12 (19.4)
Unknown	1 (0.4)	1 (1.6)
Largest Diameter (cm)	(0.4–10.0)	(0.2–4.5)	<0.001
Median (IQR)	2.5 (1.7–3.5)	1.0 (0.43–2.0)
Unknown	90 (32.0)	18 (29.0)
Location			0.27
Volar	192 (68.6)	38 (61.3)
Foot	191 (68.2)	37 (59.6)
Hand	1 (0.4)	1 (0.7)
Subungual	88 (31.4)	24 (38.7)
Histology			0.21
Acral lentiginous	260 (92.8)	60 (96.8)
Nodular	8 (2.9)	1 (1.6)
Superficial spreading	12 (4.3)	1 (1.6)
Breslow thickness (mm)			0.003
Median (IQR)	3.0 (1.7–5.0)	1.2 (0.65–2.8)
Unknown	54 (19.3)	11 (17.7)
Clark Level			<0.001
I	10 (3.6)	8 (12.9)
II/III	28 (10.0)	22 (35.5)
IV/V	164 (58.6)	18 (29.0)
Unreported/unknown	78 (27.8)	14 (22.6)
Ulceration			<0.001
Yes	185 (66.1)	18 (29.0)
No	87 (31.1)	44 (71.0)
Unreported/unknown	8 (2.8)	-
SLN biopsy			N/A
Yes	280 (100)	34 (54.8)
No	—	28 (45.2)
SLN biopsy positive			0.56
Yes	85 (30.4)	12 (35.3)
No	195 (69.6)	22 (64.7)
Number of SLN resected
Mean (SD)	3.1 (2.05)	2.0 (1.39)
CLND after SLNB+	74/85 (87)	8/12 (66.7)
Number of total LNs resected, mean (SD)	8.7 (4.35)	23.4 (12.1)
CLND positive	27/77 (35.1)	2/8 (25)	0.44
Surgery			N/A
WLE	173 (61.8)	30 (48.4)
Amputation	88 (31.4)	27 (43.5)
Mohs surgery	—	3 (4.8)
Unknown	19 (6.8)	2 (3.2)
Adjuvant therapy			N/A
Yes	238 (84.7)	4 (6.5)
No	32 (12.4)	58 (93.5)
Unreported/unknown	10 (3.9)	—