ADC |
Antibody drug conjugate |
ADCC |
Antibody-dependent cellular cytotoxicity |
AF-HPA |
Auristatin F-hydroxypropylamide |
BCN |
Bicyclononyme |
β-Me |
2-mercaptoethanol |
DDS |
Drug delivery system |
DENC |
Double emulsion nanocapsule |
DTT |
Dithiothreitol |
EBC |
Early breast cancer |
EDC |
1-ethyl-3-(3-dimethylaminopropyl) |
EGFR |
Epidermal growth factor receptor |
EMA |
European Medicines Agency |
EPR |
Enhanced permeability and retention |
FDA |
U.S. Food and Drug Administration |
GMBS |
4-maleimidobutyric acid-N hydroxysuccinimide |
GSH |
Glutathione |
HER |
Human epithermal growth factor receptor |
HSA |
Human serum albumin |
IgG |
Immunoglobulin |
MBC |
Metastatic breast cancer |
MDR |
Multidrug resistance |
MMA |
Monomethyl auristatin |
MRI |
Magnetic resonance imaging |
MTT |
Montmorillonite |
MTX |
Methotrexate |
NGM |
Next-generation maleimide |
NHS |
N-hydroxysulfosuccinimide |
NPs |
Nanoparticles |
NSCLC |
Non-small cell lung carcinoma |
PBD-MA |
Pyrrolo[2,1-c][1,4]benzodiazepine monoamide |
PD |
Pyridazinedione |
PEG |
Polyethylene glycol |
PEI |
Polyethylenimine |
PET |
Positron Emission Tomography |
Phis |
Poly-L-histidine |
PLA |
Polylactide |
PLGA |
Poly(lactic-co-glycolic acid) |
PPɣ |
Polypyrrole |
SMCC |
Succinimidyl-4-(N-maleimidomethyl)-cyclohexane-1-carboxylate |
TCEP |
Tris-2-carboxyethylphosphine |
TCO |
Trans-cyclooctene |
THP |
Tumor homing peptide |
TKI |
Tyrosine-kinase inhibitor |
Tmab |
Trastuzumab |
TPGS |
Tocopheryl polyethylene glycol succinate |
Tz |
1,2,4,5-tetrazine |
VEGFR |
Vascular endothelial growth factor receptor |
WHO |
World Health Organization |