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. 2020 Sep 29;5(40):26182–26194. doi: 10.1021/acsomega.0c03773

Table 3. IC50 Values of the Compounds 15c, 15d, and Acyclovir on the Hsp90α Protein.

compd no.a 100 (μg/mL) 10 (μg/mL) 1 (μg/mL) 0.1 (μg/mL) IC50 (μg/mL)
15c 72.742% 48.686% 26.135% 8.4154% 10.25 ± 0.30
15d 89.892% 57.424% 25.873% 10.459% 4.48 ± 0.12
acyclovir 84.063% 52.339% 35.451% 11.242% 4.78 ± 0.18
15c/acyclovir 85.554% 60.166% 26.411% 3.432% 5.22 ± 0.14
15d/acyclovir 87.314% 62.996% 44.340% 18.436% 2.26 ± 0.16
a

All data were taken as the average of three measurements.