Table 3. IC50 Values of the Compounds 15c, 15d, and Acyclovir on the Hsp90α Protein.
compd no.a | 100 (μg/mL) | 10 (μg/mL) | 1 (μg/mL) | 0.1 (μg/mL) | IC50 (μg/mL) |
---|---|---|---|---|---|
15c | 72.742% | 48.686% | 26.135% | 8.4154% | 10.25 ± 0.30 |
15d | 89.892% | 57.424% | 25.873% | 10.459% | 4.48 ± 0.12 |
acyclovir | 84.063% | 52.339% | 35.451% | 11.242% | 4.78 ± 0.18 |
15c/acyclovir | 85.554% | 60.166% | 26.411% | 3.432% | 5.22 ± 0.14 |
15d/acyclovir | 87.314% | 62.996% | 44.340% | 18.436% | 2.26 ± 0.16 |
All data were taken as the average of three measurements.