Table 5.
MIC values of the 48 Pasteurella multocida isolates grouped into six clusters after a hierarchical clustering analysis for the 12 antimicrobials tested.
| Cluster | Isolate nr | MIC | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Flor | Enrof | Amox | Marb | Ceft | Sulf | Tild | Dox | Oxitet | Tia | Tulat | Tilm | ||
| 1 | 38 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 4 | 0.5 | 0.25 | 0.5 | 16 | 1 | 2 |
| 27 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 4 | 0.5 | 0.5 | 0.5 | 16 | 1 | 2 | |
| 22 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 4 | 0.5 | 0.5 | 0.5 | 16 | 1 | 4 | |
| 40 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 4 | 0.5 | 0.5 | 0.5 | 16 | 1 | 4 | |
| 25 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 4 | 0.5 | 0.5 | 1 | 16 | 1 | 4 | |
| 26 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 4 | 0.5 | 0.5 | 1 | 16 | 1 | 4 | |
| 34 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 4 | 0.5 | 1 | 8 | 16 | 1 | 2 | |
| 44 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 4 | 0.5 | 1 | 8 | 16 | 1 | 4 | |
| 21 | 0.5 | 0.03 | 0.25 | 0.03 | 0.12 | 4 | 0.5 | 0.25 | 0.5 | 16 | 1 | 4 | |
| 20 | 0.5 | 0.03 | 0.25 | 0.03 | 0.12 | 4 | 0.5 | 0.5 | 0.5 | 16 | 1 | 2 | |
| 35 | 0.5 | 0.03 | 0.25 | 0.03 | 0.12 | 4 | 0.5 | 1 | 8 | 16 | 1 | 2 | |
| 42 | 0.5 | 0.03 | 0.25 | 0.03 | 0.12 | 4 | 0.5 | 1 | 8 | 16 | 1 | 2 | |
| 33 | 0.5 | 0.03 | 0.25 | 0.03 | 0.12 | 4 | 1 | 1 | 8 | 16 | 1 | 2 | |
| 43 | 0.5 | 0.03 | 0.5 | 0.03 | 0.06 | 4 | 0.5 | 2 | 8 | 16 | 1 | 4 | |
| 1 | 0.5 | 0.03 | 0.5 | 0.03 | 0.12 | 4 | 0.5 | 0.5 | 1 | 16 | 1 | 2 | |
| 2 | 17 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.06 | 0.5 | 1 | 2 | 2 | 1 | 2 |
| 45 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.06 | 0.5 | 2 | 2 | 8 | 0.5 | 4 | |
| 3 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.06 | 1 | 2 | 4 | 8 | 1 | 8 | |
| 36 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.25 | 0.5 | 0.25 | 0.5 | 16 | 1 | 4 | |
| 29 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.06 | 1 | 2 | 2 | 16 | 1 | 8 | |
| 18 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 1 | 1 | 2 | 2 | 16 | 1 | 8 | |
| 19 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 1 | 1 | 2 | 2 | 16 | 1 | 8 | |
| 2 | 0.5 | 0.03 | 0.5 | 0.03 | 0.06 | 0.06 | 1 | 2 | 4 | 16 | 2 | 8 | |
| 31 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.25 | 2 | 1 | 2 | 16 | 2 | 16 | |
| 32 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.06 | 2 | 0.5 | 0.5 | 16 | 4 | 16 | |
| 46 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 1 | 1 | 0.25 | 0.5 | 32 | 1 | 8 | |
| 8 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 2 | 1 | 1 | 8 | 32 | 1 | 16 | |
| 41 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.06 | 2 | 2 | 2 | 32 | 2 | 16 | |
| 24 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.06 | 2 | 2 | 8 | 32 | 2 | 16 | |
| 28 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 0.25 | 2 | 2 | 2 | 32 | 2 | 8 | |
| 16 | 0.5 | 0.03 | 0.25 | 0.03 | 0.06 | 1 | 2 | 2 | 4 | 32 | 2 | 8 | |
| 48 | 0.5 | 0.03 | 0.25 | 0.06 | 0.06 | 0.06 | 1 | 1 | 2 | 16 | 2 | 8 | |
| 4 | 0.5 | 0.03 | 0.5 | 0.03 | 0.06 | 0.06 | 2 | 2 | 2 | 8 | 2 | 16 | |
| 6 | 0.5 | 0.03 | 0.5 | 0.03 | 0.06 | 0.06 | 2 | 1 | 8 | 16 | 2 | 8 | |
| 39 | 0.5 | 0.03 | 0,5 | 0.03 | 0.06 | 0.12 | 2 | 0.5 | 0.5 | 32 | 2 | 8 | |
| 47 | 0.5 | 0.03 | 0,5 | 0.03 | 0.06 | 0.06 | 4 | 0.5 | 1 | 32 | 4 | 32 | |
| 30 | 0.5 | 0.06 | 0.12 | 0.12 | 0.06 | 0.06 | 1 | 1 | 2 | 8 | 1 | 4 | |
| 10 | 0.5 | 0.06 | 0.25 | 0.06 | 0.12 | 0.5 | 2 | 0.5 | 0.5 | 32 | 4 | 8 | |
| 9 | 0.5 | 0.06 | 0.25 | 0.12 | 0.06 | 1 | 2 | 0.25 | 0.5 | 32 | 4 | 16 | |
| 23 | 0.5 | 0.12 | 0.25 | 0.12 | 0.12 | 0.06 | 1 | 0.5 | 1 | 32 | 2 | 8 | |
| 3 | 5 | 0.5 | 0.03 | 8 | 0.03 | 0.06 | 0.25 | 2 | 1 | 8 | 16 | 4 | 16 |
| 4 | 7 | 0.5 | 0,03 | 0.5 | 0.03 | 0.25 | 0.12 | 0.5 | 0.5 | 1 | 16 | 2 | 4 |
| 14 | 0.5 | 0.25 | 0.25 | 0.25 | 0.12 | 0.12 | 0.5 | 0.5 | 0.5 | 16 | 1 | 4 | |
| 12 | 0.5 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 1 | 0.5 | 0.5 | 16 | 2 | 8 | |
| 15 | 0.5 | 0.25 | 0.5 | 0.25 | 0.12 | 0.12 | 0.5 | 0.5 | 1 | 16 | 2 | 4 | |
| 13 | 0.5 | 0.25 | 0.5 | 0.5 | 0.25 | 0.12 | 0.5 | 0.5 | 1 | 16 | 2 | 4 | |
| 5 | 37 | 0.5 | 0.5 | 0.25 | 0.5 | 0.06 | 0.06 | 1 | 2 | 4 | 32 | 2 | 8 |
| 6 | 11 | 2 | 0.5 | 0.25 | 0.5 | 0.12 | 0.25 | 64 | 8 | 8 | 16 | 64 | 64 |
Flor: florfenicol; enrof: enrofloxacin; amox: amoxicillin; marb: marbofloxacin; ceft: ceftiofur; tild: tildipirosin; dox: doxycycline; oxitet: oxitetracycline; tia: tiamulin; tulat: tulathromycin; tilm: tilmicosin.