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. 2020 Sep 3;10(9):1743. doi: 10.3390/nano10091743

Figure 8.

Figure 8

Effect of CaP with and without Ale, Dic, HR, on (A) interleukin (IL)-1β and (B) IL-10 in co-culture systems (osteoblasts-macrophages) treated with lipopolysaccharide (LPS) (1 μg/mL). Measurements were performed 3 days after LPS (1 μg/mL) stimulation. The exposure of cells to materials with and w/o Ale, Dic, and HR started 24 h before the inflammatory insult. Results (expressed as picograms per mL of supernatant) are mean ± dev.st. of three independent experiments (n = 6). (A) # p < 0.001 vs. control; ° p < 0.01 vs. LPS (1 μg/mL); § p < 0.01 vs. CaP alone. # p < 0.001 vs. control; * p < 0.05 vs. LPS (1 μg/mL); § p < 0.01 vs. CaP alone and § p < 0.01 vs. CaP+LPS (1 μg/mL). # p < 0.001 vs. control; ° p < 0.01 vs. LPS (1 μg/mL); § p < 0.01 vs. CaP alone and * p < 0.05 vs. CaP+LPS (1 μg/mL). (B) § p < 0.01 vs. CaP alone. * p < 0.05 vs. LPS (1 μg/mL); § p < 0.001 vs. CaP alone and § p < 0.001 vs. CaP+LPS (1 μg/mL). § p < 0.01 vs. CaP alone.