Table 7.
Biochemical analysis after BER and LP-BER administration. In vivo toxicity of BER and LP-BER compared to untreated control mice after 10-days i.p. administration.
| Parameter | Control | BER | LP-BER |
|---|---|---|---|
| ALT (U/L) | 94.7 ± 23.7 | 61.0 ± 12.2 | 60.8 ± 42.9 |
| AST (U/L) | 120.6 ± 16.4 | 105.2 ± 14.1 | 88.3 ± 24.2 |
| BUN (mg/dL) | 41.8 ± 7.3 | 26.0 ± 4.0 ** | 29.8 ± 3.0 |
| LDH (U/L) | 366.8 ± 55.4 | 372.5 ± 108.6 | 457.8 ± 245.3 |
| TRIG (mg/dL) | 109.5 ± 15.4 | 89.1 ± 25.1 | 70.3 ± 21.6 * |
| CHO (mg/dL) | 114.3 ± 8.5 | 111.4 ± 4.8 | 116.8 ± 16.3 |
| HDL (mmol/L) | 2.7 ± 0.1 | 2.6 ± 0.1 | 2.2 ± 0.3 |
| LDL (mmol/L) | 0.4 ± 0.1 | 0.5 ± 0.1 | 1.3 ± 0.6 |
Abbreviations: ALT—alanine aminotransferase; AST—aspartate aminotransferase; BUN—urea; LDH—lactate dehydrogenase; TRIG—triglycerides; CHO—cholesterol; HDL—high-density lipoprotein; LDL—low-density lipoprotein. Results expressed as mean ± SD (n = 6 per group). Data analyzed by Kruskal–Wallis test followed by Dunn’s multiple comparisons test. * p < 0.05, ** p < 0.01.