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L. johnsonii L531 restricts NLRP3 inflammasome activity and weakens the inhibitory effect of E. coli on autophagy through promoting ATG5/ATG16L1-mediated autophagy. L. johnsonii L531 attenuates E. coli-induced inflammation and cell damage through restricting NLRP3 inflammasome activity and promoting ATG5/ATG16L1-mediated autophagy in PMECs. Full lines represent the results of the present study, and dashed lines represent the conclusions drawn in other studies.
