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. 2020 Aug 26;9(9):541. doi: 10.3390/antibiotics9090541

Table 2.

Advantages of yeast expression systems.

Advantages Disadvantages
High yield N or O-linked glycosylation pattern (different from higher eukaryote)
Hypermannosylation
Proteolytic degradation
Stable production strains
Durability
Cost-effective
High-density growth
High productivity
Suitable for isotopically labeled protein production
Rapid growth in chemically defined media
Product processing similar to mammalian cells
Can handle S–S-rich proteins
Can assist in protein folding
Can glycosylate proteins