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Comparison of yields of proteins tagged with different signal peptides produced in the periplasm of E. coli.
| Fusion Protein | Yield (mg/L) | Disulfide Bond Number | Tag Size (kDa) | Ref |
|---|---|---|---|---|
| YkgR-BD | ~25 | 3 | 4 | [123] |
| YkgR-Hep | ~17 | 4 | 4 | [123] |
| YkgR-DkTx | ~8 | 6 | 4 | [123] |
| YoaJ-ASPA | ~5 | 3 | 2.69 | [123] |
| YoaJ-BD | ~10 | 3 | 2.69 | [123] |
| DsbA-scFv | 0.3 | 23.5 | [124] | |
| MBP-nanobodies | 2.2 | 42 | [125] | |
| DsbC-Huwentoxin | 0.7 | 23.5 | [126] | |
| pelB-human growth hormone | 1.4 | 2.31 | [127] |
