Table 2.
Top 25 most-abundant proteins present in the protein corona surrounding C3(C16His)2/MOG-siRNA lipoplexes surfaces at α = 0.2 and ρeff = 10.
Protein Number | Description | % |
---|---|---|
1 | Apolipoprotein A-I | 12.85 |
2 | Apolipoprotein A-II | 7.39 |
3 | Serum albumin | 5.38 |
4 | Ig kappa constant | 3.73 |
5 | Ig lambda constant 2 | 3.13 |
6 | Alpha-1-antitrypsin SV = 3 | 2.97 |
7 | Alpha-1-antitrypsin SV = 1 | 2.94 |
8 | Apolipoprotein A-IV | 2.90 |
9 | Complement C3 | 2.89 |
10 | Apolipoprotein E | 1.99 |
11 | Apolipoprotein C-III | 1.81 |
12 | Complement C4-B | 1.72 |
13 | Complement C4-A | 1.67 |
14 | Ig heavy constant mu | 1.62 |
15 | Trypsin | 1.54 |
16 | Apolipoprotein C-I | 1.35 |
17 | Retinol-binding protein 4 | 1.34 |
18 | APOC4-APOC2 readthrough (NMD candidate) | 1.31 |
19 | Serotransferrin | 1.25 |
20 | Apolipoprotein B-100 | 1.22 |
21 | SAA2-SAA4 readthrough | 1.19 |
22 | Haptoglobin | 1.17 |
23 | Vitronectin | 1.10 |
24 | Isoform 2 of Clusterin | 1.09 |
25 | Ig lambda-like polypeptide 5 | 1.05 |