Table 3.
Comparison of outcomes among patients receiving acute treatments for stroke
| 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | P value | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptomatic ICH | IVT* | 60 (5.8) | 76 (5.1) | 83 (3.8) | 107 (4.4) | 97 (3.5) | 166 (3.5) | 185 (3.3) | 161 (3.0) | 200 (3.2) | 234 (3.3) | 215 (2.8) | <0.001 |
| IAT* | 8 (5.8) | 14 (6.6) | 18 (6.3) | 13 (3.1) | 18 (4.0) | 25 (4.5) | 27 (3.5) | 49 (4.0) | 61 (3.9) | 82 (3.8) | 159 (4.9) | 0.72 | |
| IVT+IAT* | 6 (12.8) | 3 (4.1) | 14 (11.3) | 14 (8.8) | 15 (6.9) | 10 (3.5) | 14 (4.0) | 37 (5.7) | 46 (5.9) | 54 (4.9) | 69 (5.4) | 0.038 | |
| Life-threatening complications | IVT* | 14 (1.4) | 12 (0.8) | 19 (0.9) | 18 (0.7) | 19 (0.7) | 36 (0.8) | 32 (0.6) | 33 (0.6) | 39 (0.6) | 39 (0.5) | 43 (0.6) | 0.002 |
| IAT* | 1 (0.7) | 1 (0.5) | 2 (0.7) | 5 (1.2) | 2 (0.4) | 2 (0.4) | 4 (0.5) | 6 (0.5) | 7 (0.4) | 5 (0.2) | 25 (0.8) | NA | |
| IVT+IAT* | 1 (2.1) | 3 (4.1) | 3 (2.4) | 2 (1.3) | 0 | 5 (1.7) | 5 (1.4) | 7 (1.1) | 4 (0.5) | 10 (0.9) | 15 (1.2) | NA | |
| In-hospital mortality | IVT* | 72 (7.0) | 121 (8.2) | 174 (8.1) | 170 (7.0) | 156 (5.7) | 326 (6.9) | 324 (5.8) | 269 (5.0) | 304 (4.9) | 314 (4.4) | 297 (3.9) | <0.001 |
| IAT* | 17 (12.2) | 37 (17.5) | 45 (15.8) | 77 (18.5) | 61 (13.7) | 75 (13.6) | 80 (10.4) | 180 (14.7) | 231 (14.6) | 288 (13.2) | 441 (13.5) | 0.09 | |
| IVT+IAT* | 4 (8.5) | 20 (27.0) | 21 (16.9) | 29 (18.1) | 24 (11.1) | 36 (12.5) | 34 (9.6) | 64 (9.9) | 92 (11.7) | 132 (12.1) | 137 (10.8) | 0.005 | |
| Able to ambulate independently at discharge | IVT* | 341 (33.2) | 529 (35.7) | 747 (34.6) | 902 (37.1) | 1111 (40.3) | 1868 (39.7) | 2349 (42.4) | 2609 (48.1) | 3021 (48.4) | 3801 (52.8) | 4078 (53.4) | <0.001 |
| IAT* | 29 (20.9) | 44 (20.8) | 49 (17.3) | 85 (20.4) | 95 (21.3) | 127 (23.0) | 225 (29.2) | 373 (30.4) | 453 (28.7) | 638 (29.2) | 948 (29.1) | <0.001 | |
| IVT+IAT* | 15 (31.9) | 11 (14.9) | 20 (16.1) | 37 (23.1) | 60 (27.8) | 73 (25.3) | 128 (36.2) | 233 (36.1) | 276 (35.2) | 403 (36.9) | 485 (38.1) | <0.001 | |
| Discharge home | IVT* | 248 (24.2) | 423 (28.6) | 755 (35.0) | 894 (36.8) | 1030 (37.3) | 2000 (42.5) | 2469 (44.6) | 2685 (49.5) | 3123 (50.0) | 3749 (52.1) | 4151 (54.3) | <0.001 |
| IAT* | 23 (16.5) | 42 (19.8) | 54 (19.0) | 78 (18.8) | 85 (19.1) | 123 (22.3) | 218 (28.3) | 301 (24.5) | 375 (23.8) | 559 (25.6) | 800 (24.5) | <0.001 | |
| IVT+IAT* | 7 (14.9) | 8 (10.8) | 16 (12.9) | 37 (23.1) | 50 (23.1) | 75 (26.0) | 117 (33.1) | 221 (34.2) | 259 (33.0) | 360 (33.0) | 457 (35.9) | <0.001 |
*
Treatment given at a participating hospital.
IAT, intra-arterial treatment; ICH, intracranial hemorrhage; IVT, intravenous thrombolysis.