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. 2020 Sep 16;9(9):755. doi: 10.3390/pathogens9090755

Figure 1.

Figure 1

Study flow chart. Values are given as median (interquartile range (IQR)) or n (%). In contrast to anti-nuclear antibodies (ANAs), cryoglobulins were present in patients with overt hepatitis E (acute and chronic hepatitis E), but not in any of the covert hepatitis E virus (HEV) infections (chi-square, p = 0.02). Total serum IgG levels did not differ significantly between overt/covert HEV infection (Mann-Whitney-U-test, p = 0.2). Cryoglobulins were significantly detected more often in chronic hepatitis E, compared with acute self-limiting HEV infection (p = 0.014).