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. 2020 Sep 17;5(3):45. doi: 10.3390/biomimetics5030045

Table 1.

Antimicrobial testing of antibiotics (A), AV-PVP-I2 (+), AV-PVP-I2-NaI (++), and dilutions. ZOI (mm) against microbial strains by disc diffusion assay as dilution series.

Strain Antibiotic A 1+ 2+ 3+ 4+ 1++ 2++ 3++ 4++
S. pneumoniae ATCC 49619 G 21 14 12 10 0 13 0 0 0
S. aureus ATCC 25923 G 28 25 20 19 8 20 13 11 0
S. pyogenes ATCC 19615 C 25 16 10 0 0 10 0 0 0
E. faecalis ATCC 29212 CTX 25 17 12 9 0 0 0 0 0
B. subtilis WDCM 00003 S 20 22 17 10 0 16 11 8 0
P. mirabilis ATCC 29906 G 35 0 0 0 0 0 0 0 0
P. aeruginosa WDCM 00026 CTX 20 13 0 0 0 9 8 0 0
E. coli WDCM 00013 G 23 18 13 11 0 12 10 8 0
K. pneumoniae WDCM 00097 CTX 35 23 14 11 0 11 8 0 0
C. albicans WDCM 00054 NY 16 56 20 17 11 35 28 25 17 **

Disc diffusion studies (6 mm disc impregnated with 2 mL of 50 µg/mL (1), 2 mL of 25 µg/mL (2) and 2 mL of 12.5 µg/mL (3), and 2 mL of 6 µg/mL (4) of compounds AV-PVP-I2 (+) and AV-PVP-I2-NaI (++)). G Gentamicin (30 µg/disc). CTX (Cefotaxime) (30 µg/disc). NY (Nystatin) (100 IU). C Chloramphenicol (10 µg/disc). Streptomycin (10 µg/disc) Grey shaded area represents Gram-negative bacteria. 0 = Resistant. No statistically significant differences (p > 0.05) between row-based values through Pearson correlation. ** Compound M4 was diluted to 3 µg/mL (5) and achieved ZOI = 9.