Table 1.
Strain | Antibiotic | A | 1+ | 2+ | 3+ | 4+ | 1++ | 2++ | 3++ | 4++ |
---|---|---|---|---|---|---|---|---|---|---|
S. pneumoniae ATCC 49619 | G | 21 | 14 | 12 | 10 | 0 | 13 | 0 | 0 | 0 |
S. aureus ATCC 25923 | G | 28 | 25 | 20 | 19 | 8 | 20 | 13 | 11 | 0 |
S. pyogenes ATCC 19615 | C | 25 | 16 | 10 | 0 | 0 | 10 | 0 | 0 | 0 |
E. faecalis ATCC 29212 | CTX | 25 | 17 | 12 | 9 | 0 | 0 | 0 | 0 | 0 |
B. subtilis WDCM 00003 | S | 20 | 22 | 17 | 10 | 0 | 16 | 11 | 8 | 0 |
P. mirabilis ATCC 29906 | G | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
P. aeruginosa WDCM 00026 | CTX | 20 | 13 | 0 | 0 | 0 | 9 | 8 | 0 | 0 |
E. coli WDCM 00013 | G | 23 | 18 | 13 | 11 | 0 | 12 | 10 | 8 | 0 |
K. pneumoniae WDCM 00097 | CTX | 35 | 23 | 14 | 11 | 0 | 11 | 8 | 0 | 0 |
C. albicans WDCM 00054 | NY | 16 | 56 | 20 | 17 | 11 | 35 | 28 | 25 | 17 ** |
Disc diffusion studies (6 mm disc impregnated with 2 mL of 50 µg/mL (1), 2 mL of 25 µg/mL (2) and 2 mL of 12.5 µg/mL (3), and 2 mL of 6 µg/mL (4) of compounds AV-PVP-I2 (+) and AV-PVP-I2-NaI (++)). G Gentamicin (30 µg/disc). CTX (Cefotaxime) (30 µg/disc). NY (Nystatin) (100 IU). C Chloramphenicol (10 µg/disc). Streptomycin (10 µg/disc) Grey shaded area represents Gram-negative bacteria. 0 = Resistant. No statistically significant differences (p > 0.05) between row-based values through Pearson correlation. ** Compound M4 was diluted to 3 µg/mL (5) and achieved ZOI = 9.