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. 2020 Sep 14;13(9):245. doi: 10.3390/ph13090245

Figure 5.

Figure 5

Homogeneous SDC (scFv-drug conjugate) with a DAR 1 obtained by reduction (TCEP) of the C-terminal intrachain disulfide bridge followed by a site-specific bioconjugation reaction via a dithiophenylmaleimide linker (DSPh).