Table 1.
Size and zeta potential characterization of fusogenic liposomes (FL) and polyethylene glycol (PEG)ylated endocytic liposomes (PEG-EL) loaded with the anthracyclines ACL and DOX and corresponding encapsulation efficiencies (EE) determined by filtration. Mean with standard deviation is shown.
| Size (nm) | ζ Potential (mV) | EE (%) | |
|---|---|---|---|
| FL | 116 ± 45 | 70 ± 6 | - |
| FL-ACL | 87 ± 14 | 64 ± 25 | 92 ± 6 |
| FL-DOX | 85 ± 4 | 69 ± 5 | 88 ± 6 |
| PEG-EL | 163 ± 78 | −29 ± 18 | - |
| PEG-EL-ACL | 152 ± 46 | −47 ± 5 | 89 ± 4 |
| PEG-EL-DOX | 142 ± 44 | −48 ± 10 | 90 ± 6 |