Table 4.
Males | Females | ||||||
---|---|---|---|---|---|---|---|
OR | 95%CI | p | OR | 95%CI | p | ||
Model 1 | |||||||
HHcy−/MetS− | Reference | Reference | |||||
HHcy−/MetS+ | 1.238 | 1.046–1.466 | 0.013 | 1.273 | 1.064–1.523 | 0.008 | |
HHcy+/MetS− | 1.568 | 1.318–1.866 | <0.001 | 1.507 | 0.915–2.482 | 0.107 | |
HHcy+/MetS+ | 1.837 | 1.286–2.625 | <0.001 | 3.280 | 1.773–6.068 | <0.001 | |
p-for trend | <0.001 | <0.001 | |||||
Model 2 | |||||||
HHcy−/MetS− | Reference | Reference | |||||
HHcy−/MetS+ | 1.199 | 1.011–1.421 | 0.037 | 1.242 | 1.037–1.488 | 0.019 | |
HHcy+/MetS− | 1.561 | 1.311–1.858 | <0.001 | 1.469 | 0.891–2.420 | 0.132 | |
HHcy+/MetS+ | 1.769 | 1.237–2.530 | 0.002 | 3.186 | 1.719–5.904 | <0.001 | |
p-for trend | <0.001 | <0.001 | |||||
Age | 0.993 | 0.988–0.999 | 0.013 | 0.972 | 0.965–0.979 | <0.001 | |
Smoking | 0.990 | 0.913–1.073 | 0.802 | 0.900 | 0.763–1.062 | 0.212 | |
Drinking | 1.082 | 0.979–1.196 | 0.122 | 1.038 | 0.908–1.188 | 0.582 | |
Physical activity | 1.051 | 0.931–1.185 | 0.422 | 0.913 | 0.775–1.077 | 0.281 | |
hs-CRP | 1.121 | 1.019–1.233 | 0.019 | 0.948 | 0.810–1.110 | 0.509 | |
Albumin | 1.399 | 1.132–1.728 | 0.002 | 1.662 | 1.250–2.209 | 0.000 | |
HHcy+/MetS+ vs HHcy−/MetS+ | 1.456 | 0.993–2.136 | 0.055 | 2.534 | 1.353–4.747 | 0.004 | |
HHcy+/MetS+ vs HHcy+/MetS− | 1.130 | 0.767–1.665 | 0.537 | 2.241 | 1.023–4.908 | 0.044 |
p-values calculated using logistic regression. p-for trend calculated using the Cochran–Armitage trend test. Abbreviations: HHcy, hyperhomocysteinemia; MetS, metabolic syndrome; OR, odds ratio; CI, confidence interval; hs-CRP, high-sensitivity c-reactive protein. Model 1: univariate logistic regression analysis when the age was held constant. Model 2: multivariate logistic regression analysis adjusted for smoking, drinking, physical activity, hs-CRP level, and albumin level.