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. 2020 Sep 18;17(18):6810. doi: 10.3390/ijerph17186810

Table 4.

Odds of albuminuria for the presence or absence of HHcy and MetS.

Males Females
OR 95%CI p OR 95%CI p
Model 1
HHcy−/MetS− Reference Reference
HHcy−/MetS+ 1.238 1.046–1.466 0.013 1.273 1.064–1.523 0.008
HHcy+/MetS− 1.568 1.318–1.866 <0.001 1.507 0.915–2.482 0.107
HHcy+/MetS+ 1.837 1.286–2.625 <0.001 3.280 1.773–6.068 <0.001
p-for trend <0.001 <0.001
Model 2
HHcy−/MetS− Reference Reference
HHcy−/MetS+ 1.199 1.011–1.421 0.037 1.242 1.037–1.488 0.019
HHcy+/MetS− 1.561 1.311–1.858 <0.001 1.469 0.891–2.420 0.132
HHcy+/MetS+ 1.769 1.237–2.530 0.002 3.186 1.719–5.904 <0.001
p-for trend <0.001 <0.001
Age 0.993 0.988–0.999 0.013 0.972 0.965–0.979 <0.001
Smoking 0.990 0.913–1.073 0.802 0.900 0.763–1.062 0.212
Drinking 1.082 0.979–1.196 0.122 1.038 0.908–1.188 0.582
Physical activity 1.051 0.931–1.185 0.422 0.913 0.775–1.077 0.281
hs-CRP 1.121 1.019–1.233 0.019 0.948 0.810–1.110 0.509
Albumin 1.399 1.132–1.728 0.002 1.662 1.250–2.209 0.000
HHcy+/MetS+ vs HHcy−/MetS+ 1.456 0.993–2.136 0.055 2.534 1.353–4.747 0.004
HHcy+/MetS+ vs HHcy+/MetS− 1.130 0.767–1.665 0.537 2.241 1.023–4.908 0.044

p-values calculated using logistic regression. p-for trend calculated using the Cochran–Armitage trend test. Abbreviations: HHcy, hyperhomocysteinemia; MetS, metabolic syndrome; OR, odds ratio; CI, confidence interval; hs-CRP, high-sensitivity c-reactive protein. Model 1: univariate logistic regression analysis when the age was held constant. Model 2: multivariate logistic regression analysis adjusted for smoking, drinking, physical activity, hs-CRP level, and albumin level.