Figure 2.

Expression of select immune markers in human PBMCs (n = 4) exposed to antibiotics and 10 μg/mL (high) (a–d) or 1 μg/mL (low) (e–h) purified S. aureus LTA. Antibiotics include VAN, vancomycin; TED, tedizolid; DAP, daptomycin. Protein expression was determined using either flow cytometry (PD-L1, HLA-DR, TLR2) or ELISA (IL-10, TNFα). Antibiotics alone and untreated cells were used as controls. Data are displayed as means with error bars depicting standard deviation. Brackets indicate statistical comparisons between treatments: ** p < 0.01; **** p < 0.0001.