Table 1.
F.C. (%) | H. contortus | T. axei | T. colubriformis | T. circumcincta | T. vitrinus | C. oncophora | Mixed Infection |
---|---|---|---|---|---|---|---|
2% | 91.25 (4.82) a | 98.80 (0.97) a | 94.65 (2.28) a | 100 a | 100 a | 24.58 (3.62) b | 84.88 (12.14) a |
1% | 87.36 (4.46) a | 98.71 (1.05) a | 81.11 (4.80) a | 100 a | 99 (0.76) a | 15.80 (2.69) b | 80.35 (13.28) a |
0.5% | 67.77 (4.03) b | 95.65 (3.55) a | 49.79 (4.02) b | 99 (0.82) a | 92 (0.64) a | 6.40 (2.71) b | 68.44 (14.64) a |
0.25% | 38 (3.89) b | 69 (8.35) b | 12.55 (5.23) b | 95.95 (1.73) a | 61.1 (4.53) b | 2.22 (1.81) b | 46.50 (14.55) b |
0.125% | 29.14 (3.31) b | 42.21 (9.04) b | 2.22 (1.81) b | 65.33 (6.42) b | 15 (1.80) b | 0.00 b | 25.67 (10.30) b |
IC50 | 0.26 | 0.15 | 0.48 | 0.11 | 0.21 | 3.31 | 0.22 |
R2 | 0.94 | 0.93 | 0.98 | 0.98 | 0.99 | 0.88 | 0.75 |
+ve control | 87.18 (3.17) a | 87.80 (1.85) a | 91 (1.46) a | 85 (2.36) a | 93.27 (0.34) a | 94.55 (2.23) a | 89.81 (1.53) a |
–ve control | 0.00 b | 0.00 b | 0.00 b | 0.00 b | 0.00 b | 00.00 b | 00.00 b |
Data are presented as mean percentage of larval motility inhibition (± SEM). a No statistical difference between positive control and treatments (p > 0.05). b Significant difference between positive control and treatments (p < 0.05; ANOVA followed by Tukey test). Abbreviations: F.C. = Final concentration; +ve control (positive control; L3s treated with 20 mg/mL levamisole); –ve control (negative control; L3s treated with PBS-Tween 2%); IC50 = inhibitory concentration 50%; R2 = nonlinear correlation.