Table 4.
F.C. (%) | H. contortus | T. axei | T. colubriformis | T. circumcincta | T. vitrinus | C. oncophora | Mixed Infection |
---|---|---|---|---|---|---|---|
2% | 0.00 a | 0.00 a | 0.00 a | 0.00 a | 0.00 a | 30.7 (4.16) a | 0.00 a |
1% | 23.1 (3.2) a | 40 (5.7) a | 23.1 (7.6) a | 53.8 (1.5) b | 25 (2.0) a | 100 b | 40 (6.8) b |
0.5% | 46.1 (4.52) b | 60 (1.1) b | 69.2 (2.8) b | 69.2 (7.5) b | 80 (4.0) b | 53.8 (6.2) b | 66.6 (4.5) b |
0.25% | 69.2 (3.9) b | 70 (3.6) b | 100 b | 90 (2.5) b | 90 (6.1) b | 76.9 (8.3) b | 80 (4.5) b |
0.125% | 100 b | 100 b | 100 b | 100 b | 100 b | 76.9 (12.5) b | 100 b |
IC50 (%) | 0.31 | 0.36 | 0.66 | 0.56 | 0.72 | 0.15 | 0.51 |
R2 | 0.05 | 0.01 | 0.18 | 0.03 | 0.24 | 0.09 | 0.17 |
+ve control | 30.7 (1.32) a | 52.6 (1.52) a | 48.7 (2.5) a | 30.7 (2) a | 30 (2.04) a | 45.8 (2.0) a | 26.6 (6.6) a |
–ve control | 66.0 (3.7) b | 78.9 (5.2) b | 79.4 (5.3) b | 77.5 (5) b | 71.4 (4.0) b | 72.9 (2.0) b | 75 (2.2) b |
Data are presented as the normalized mean of fluorescence intensity (± SEM) and show the effect of coriander oil-linalool combination on the fluorescence uptake of C12-resazurin by live L3s. a Non-statistical difference between positive control and treatments (p > 0.05) b Significant difference between positive control and treatments (p < 0.05; ANOVA followed by Tukey test). Abbreviations: F.C. = Final concentration; +ve control (positive control; L3s treated with 50% methanol); –ve control (negative control; L3s treated with PBS-Tween 2%); IC50 = inhibitory concentration 50%; R2 = nonlinear correlation.