Table 1.

West Nile neuroinvasive disease: A single center experience.

Sex, Age (Years)	Previous Clinical History	Date of Infection	Clinical Form	Diagnosis *	Therapy	Outcome and/or Sequelae
Male, 33	Epilepsy	July 2018	VII cranial nerve palsy	Serology (IgM) in serum and LCR	Steroid	Healed
Female, 15	Previously healthy	July 2018	Fever, cephalea, Parkinsonism, left arm strength deficit, tongue fasciculation	Serology (IgM and IgG) in CSF	None	Healed
Male, 87	Ischemic cardiomyopathy	August 2018	Fever, meningismus and neuropathic pain, limbs waxy flexibility and catatonic states.	rt-PCR in both urine and CSF; serology (IgM and IgG) in both CSF and serum	IVIG and steroids	Residual disability, depression
Male, 56	Renal transplant, previous CMV and VZV reactivation	August 2018	Fever, confusion, meningismus	Serology (IgM) in serum; rt-PCR in urine	IVIG and steroids	Healed
Male, 57	Autoimmune glomerulonephritis in immunosuppressive treatment	September 2018	Rhombencephalitis, coma, intracranial hemorrhage	Serology (IgM) in serum; rt-PCR in CSF, urine and blood	IVIG and steroids	Death
Female, 78	Diabetes, hypertension, non-Hodgkin lymphoma	October 2018	Confusion, stupor, coma	rt-PCR in CSF, urine and blood		Death
Female, 77	B chronic lymphocytic leukemia, hypogammaglobulinaemia, hypertension, diabetes, previous CMV reactivation	November 2018	Fever, confusion, 4 limbs hyposthenia, acute kidney injury, coma	rt-PCR in CSF and urine	IVIG and steroids	Partial improvement, residual disability

Abbreviations—rt-PCR: reverse-transcription polymerase chain reaction, IgM: immunoglobulin M, IgG; immunoglobulin G; IVIG: intravenous immunoglobulin; CSF: cerebrospinal fluid; CMV: cytomegalovirus; VZV: varicella zoster virus. * Only positive results are reported.