Table 2.
Time course of assessment scores for two age groups.
| Age | Time Course | ||||
|---|---|---|---|---|---|
| 2 Weeks | 1 Month | 6 Months | 30 Months | ||
| MBI | 20–69 | 28.59 (20.31–32.24) | 42.33 * (38.77–52.75) | 63.98 * (60.99–73.29) | 70.58 (65.54–76.62) |
| 70–89 | 29.50 (11.61–37.44) | 45.57 * (33.32–66.51) | 50.91 (41.97–68.40) | 46.00 *,† (32.84–60.03) | |
| mRS | 20–69 | 4.33 (4.14–4.59) | 3.77 * (3.43–3.92) | 3.20 * (2.82–3.28) | 2.80 * (2.61–3.05) |
| 70–89 | 4.58 (4.30–4.99) | 4.00 * (3.32–4.42) | 3.92 (3.31–4.28) | 3.83 † (3.37–4.41) | |
| FAC | 20–69 | 0.75 (0.38–0.97) | 1.48 * (1.23–1.89) | 2.31 * (2.15–2.82) | 2.94 * (2.49–3.19) |
| 70–89 | 0.31 (0.17–0.63) | 1.00 * (0.49–1.78) | 1.50 (0.98–2.33) | 1.75 (0.89–2.37) | |
| MRCUF | 20–69 | 3.58 (2.81–4.15) | 4.13 * (3.91–5.21) | 5.53 * (5.02–6.09) | 5.86 (5.29–6.37) |
| 70–89 | 4.92 (3.19–6.36) | 4.86 (4.27–7.27) | 5.62 (4.76–7.52) | 5.79 (4.64–7.25) | |
| MRCLE | 20–69 | 4.62 (3.80–5.13) | 5.53 * (5.28–6.39) | 6.59 * (6.34–7.13) | 6.48 (6.19–6.96) |
| 70–89 | 6.08 (4.72–6.87) | 6.71 (5.53–7.92) | 6.00 (5.23–7.23) | 5.57 (4.48–6.65) | |
| MMSE | 20–69 | 14.15 (10.98–15.34) | 17.33 * (14.62–18.98) | 19.93 * (19.40–23.20) | 20.76 (19.81–23.40) |
| 70–89 | 14.22 (8.06–17.49) | 17.11 * (13.64–20.71) | 17.10 (13.92–20.12) | 15.36 † (13.07–17.61) | |
Data are expressed as the mean (95% confidence interval). MBI, Modified Barthel Index; mRS, modified Rankin Scale; FAC, functional ambulation category; MRCUF, sum of MRC scores for elbow and wrist flexion of affected arm; MRCLE, sum of MRC scores for hip and knee extension of affected leg; MMSE, Mini-Mental State Examination. All functional scores were compared between two age groups at 2 weeks, 1 month, 6 months, and 30 months, using generalized estimated equation analysis. Pairwise comparison was performed using estimated marginal means to identify a within-patient time effect or between-patients group effect. The p-value was adjusted based on Bonferroni correction for multiple comparisons in post hoc analysis. * Adjusted p-value < 0.05 for within-patient time effect; pairwise comparison with former score for time. † Adjusted p-value < 0.05 for between-patients group effect; pairwise comparison with adjacent score for age group.