Skip to main content
. Author manuscript; available in PMC: 2021 Oct 9.
Published in final edited form as: ACS Infect Dis. 2020 Sep 21;6(10):2616–2628. doi: 10.1021/acsinfecdis.0c00217

Scheme 1. JMX0207 Synthesis Routea.

Scheme 1.

aReagents and conditions: (a) CH3I, K2CO3, DMF, 50 °C, 24 h, 95%; (b) NaOH, H2O/MeOH, r.t., 1 h, 93%; (c) 2-chloro-4-nitroaniline, POCl3, pyridine, DCM, 0 °C to r.t., 8 h, 67%; (d) BBr3, DCM, 0 °C to r.t., 12 h, 96%.