ASGPR	Asialoglycoprotein receptor
ASOs	Antisense oligonucleotides
Cas9	CRISPR-associated protein 9
cLNPs	cLNP constrained lipid nanoparticles
cMBP2	c-Met-binding peptide
CPPs	cell-penetrating peptides
CRC	Cysteine–arginine–cysteine
DBCO	Dibenzocyclooctyne amine
ddPCR	digital droplet PCR
DSB	double-strand break
DTNB	5,5′-Dithio-bis(2-nitrobenzoic acid)
ECO	1-aminoethyl)iminobis[N-(oleicylcysteinyl-1-amino-ethyl)propionamide]
EG5	Eglin-5
EHCO	(1-aminoethyl) imino bis [N-(oleoyl cysteinyl histinyl-1-aminoethyl) propionamide]
EGFR	Epidermal growth factor receptor
EPR	Enhanced permeation and retention
ESC	Enhanced stabilization chemistry
Fmoc	Fluorenyl methoxycarbonyl
FolA	Folic acid
FR	Folate receptor
FRET	Fluorescence resonance energy transfer
GSH	Glutathione
INF7	glutamic acid-enriched analogue of the influenza hemagglutinin membrane protein HA2
LNPs	Lipid nanoparticles
LPEI	linear PEI
mRNA	Messager RNA
MTX	Methotrexate
NIS	Sodium iodide symporter
NLS	Nuclear localization signal
NPC	Nuclear pore complex
OAAs	Oligoaminoamides
OPSS	ortho-pyridyl disulfide
PAs	Peptide amphiphiles
pDNA	Plasmid DNA
PEG	Polyethylene glycol
PEI	Polyethylenimine
pHPMA	poly(N-(2-hydroxypropyl)methacrylamide)
pING4	pDNA encoding inhibitor of growth 4
PMOs	Phosphorodiamidate morpholino oligonucleotides
PT	Pretubulysin
RAFT	Reversible addition-fragmentation chain transfer
RISC	RNA-induced silencing complex
RNAi	RNA interference
RNP	Ribonucleoprotein
SCOs	splice-correcting oligonucleotides
sgRNA	single guide RNA
siRNA	Small interfering RNA
Stp	Succinoyltetraethylene-pentamine
Sph	Succinoyl-pentaethylene hexamine
SPS	Solid phase supported synthesis
SSBB	Disulfide building block = succinoyl-cystamine
tBoc	t-butyloxycarbonyl
TCPs	Targeted combinatorial polyplexes
TLPs	Targeted lipopolyplexes
TNBC	triple-negative breast cancer
Tf	Transferrin
TfR	Transferrin receptor
TTR	Transthyretin