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. 2020 Sep 16;9(9):753. doi: 10.3390/pathogens9090753

Figure 2.

Figure 2

Gut microbiome composition differs in mouse models of TRPA1 knockout, TRPV1 knockout and TRPA1/V1 double-knockout as compared to each other as well as to their TRP wild-type counterparts. (a) Gut microbiome composition at bacterial phylum level; (b–d) the abundance of major phyla; (e) ratio of Firmicutes to Bacteroides and (f) ratio of Gram-positive to Gram-negative taxa; (g) ratio of anaerobic to aerobic bacteria; and (h,i) microbiome composition at the level of major bacterial families (h) and genera (i); and (j,k) proportion of potentially pathogenic bacteria (j) and biofilm forming bacteria (k), in the mouse models of TRPA1 KO, TRPV1 KO and TRPA1/V1 dKO versus TRP-WT counterparts. * p < 0.05, ** p < 0.001.