Figure 3.

Differences in the abundance of various gut bacteria in mouse models of TRPA1 knockout, TRPV1 knockout and TRPA1V1 double-knockout as compared to each other as well as to the TRP wild-type counterparts. (a,b) Hierarchical clustering heap-map depicting distinct arrays characterized by different abundance levels (a) and Log₂ fold-differences (b) of major gut bacterial phyla, families and genera in mouse models of TRPA1 KO, TRPV1 KO and TRPA1/V1 dKO versus TRP-WT counterparts. (c,d) Major gut bacterial phyla, families and genera that were found to be reduced (c) or increased (d) in all of the three mouse models i.e., A1 KO, V1KO and A1V1dKO versus TRP-WT counterparts.