Table 1.
Immunocompromised patients infected with the dual H275Y mutant influenza A(H1N1)pdm09 viruses.
| Isolate Name | Date of Symptom Onset (Day/Month/Year) |
Antiviral Administration (Day/Month/Year) |
Date of Specimen Collection (Day/Month/Year) |
NA Substitution |
|---|---|---|---|---|
| A/Hiroshima/57/2014 | 31-03-2014 | 31-03-2014: Peramivir 04-04-2014: Laninamivir |
04-04-2014 | H275Y/I223R |
| A/Ibaraki/54/2016 | 09-02-2016 | 09-02-2016: Peramivir 24-02-2016 to 03-03-2016: Peramivir 26-02-2016 to 03-03-2016: Oseltamivir 05-03-2016: Laninamivir |
07-03-2016 | H275Y/I223K |
| A/Hiroshima/13/2016 | 26-02-2016 | 23-02-2016: Laninamivir 26-02-2016 to 01-03-2016: Peramivir 07-03-2016 to 11-03-2016: Peramivir 28-03-2016 to 01-04-2016: Peramivir |
11-03-2016 | H275Y/G147R |
NA: neuraminidase.