Table 2.

Mutation frequency in HbH disease patients

Mutation	Type	Frequency	%
--MED	Deletion	33	37.5
-α3.7	Deletion	31	35.2
α2poly-A1 (AATAAA>AATAAG)	Point mutation	14	15.9
-α4.2	Deletion	3	3.4
-α20.5	Deletion	2	2.3
Codon 59 (GGC > GAC) (Hb Adana)	Point mutation	2	2.3
α2 IVS-I(−5 nt) (−TGAGG)	Splicing site 5 nt. Deletion	2	2.3
α2poly-A2 (AATAAA>AATGAA)	Point mutation	1	1.1
Total		88	100