Table 2.
Results of subgroup and meta-regression analyses
| Subgroup | Studies | HR (95%CI) | P-value | Heterogeneity (I2) |
Pheterogeneity | Meta-regression (P-value) |
|---|---|---|---|---|---|---|
| Sample source | P = 0.993 | |||||
| Serum | 5 | 1.52 (0.75–3.10) | P = 0.250 | 86.5% | P < 0.001 | |
| Tissue | 6 | 1.57 (1.06–2.32) | P = 0.023 | 59.0% | P = 0.032 | |
| Sample size | P = 0.078 | |||||
| Large(> 100) | 5 | 2.05 (1.07–2.24) | P < 0.001 | 0.0% | P < 0.001 | |
| Small(< 100) | 6 | 1.24 (0.66–2.31) | P = 0.506 | 85.2% | P = 0.899 | |
| Ethnicity | P = 0.080 | |||||
| Asian | 7 | 1.28 (0.74–2.21) | P = 0.384 | 82.3% | P < 0.001 | |
| Non-Asian | 4 | 2.08 (1.56–2.77) | P < 0.001 | 0.0% | P = 0.709 |