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. 2020 Aug 5;8(3):87. doi: 10.3390/dj8030087

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(a), Estimated mean ± 95% confidence intervals (CIs) for component 1 variable importance parameter (VIP) values for each potential “predictor” variable included in the multivariate PLS-R analysis model applied to the sample size-weighted systematic review dataset. VIP values are considered statistically significant if the lower 95% CI is >1.00, and therefore only treatment option (1 or 2) was found to be a significant contributory variable towards clinical outcome score. (b) Plot of mean ± 95% CI values for the two treatment options obtained from the univariate ANCOVA of the full dataset. Treatments 1 and 2 correspond to pre- and post-laser treatment options, respectively.