Figure 1.

Anatomical Localization of Area V6A, Experimental Design, and Mathematical Model

(A) Three-dimensional reconstruction of macaque brain. Dorsal view of the left hemisphere and medial view of the right hemisphere showing area V6A in yellow (Galletti et al., 1999). cal, calcarine sulcus; cs, central sulcus; ips, intraparietal sulcus; ls, lunate sulcus; pos, parieto-occipital sulcus; sts, superior temporal sulcus; D, dorsal; P, posterior; A, anterior; L, lateral.

(B) Experimental setup. Reach movements were performed in darkness toward 1 of 9 LEDs (orange) arranged over a panel mounted at eye level in front of the monkey. Spatial coordinates of targets are indicated as vergence and version angles with respect to the eyes. HB: Home Button.

(C) Task sequence. From left to right: trial start (HB press), target appearance (LEDon), fixation onset (end of saccade, Fix), go signal (Go), start of the arm movement (M1), touch and holding of the target (Touch), LED switch-off (REDoff) return movement (M2). Color bar below the drawings illustrate the epochs considered in the model. DELAY epoch overlaps with POSTSACC and PREP.

(D) Schematic representation of the Generalized Linear model. Behavioral data are used to build the matrix of regressors (X, independent variables). Recorded neural activity is used to build the vector of μ_OBS (dependent variable). X and μ_OBS are used to fit the model and estimate the vector of beta coefficients (β). μ_EST can be reconstructed with X and the estimated β passing through an exponential function.