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. 2020 Sep 11;12(9):866. doi: 10.3390/pharmaceutics12090866

Table 3.

ANOVA for the 23 factorial design of SV-loaded nano-spanlastics.

Dependent Variable Source Sum of Squares df Mean Square F-Value p-Value
EE% (Y1) Model 631.81 3 210.65 48.23 0.0013
X1 535.79 1 535.79 122.71 0.0004
X2 37.54 1 37.54 8.60 0.0427
X3 58.45 1 58.48 13.39 0.0216
Q12h (Y2) Model 481.10 3 160.37 25.98 0.0044
X1 95.36 1 95.36 15.45 0.0171
X2 212.39 1 212.39 34.41 0.0042
X3 173.35 1 173.35 28.08 0.0061

Notes: X1: Ratio of Span 60 to EA, X2: Type of EA, X3: Rotation speed (rpm), p-value less than 0.05 indicates model terms are significant. Abbreviations: EE, entrapment efficiency; Q12h, drug released after 12h.