Table 1.
Cayman chemical epigenetics screening library
| Plate 1 | Plate 2 | ||
|---|---|---|---|
| Well | Small molecule | Well | Small molecule |
| A2 | 3-amino benzamide | A2 | AGK2 |
| A3 | SB 939 | A3 | CAY10603 |
| A4 | PCI 34051 | A4 | Chaetocin |
| A5 | 4-iodo-SAHA | A5 | Splitomicin |
| A6 | Sirtinol | A6 | CBHA |
| A7 | C646 | A7 | M 344 |
| A8 | Ellagic acid | A8 | Oxamflatin |
| A9 | Scriptaid | A9 | Salermide |
| A10 | Suberohydroxamic acid | A10 | Mirin |
| A11 | Apicidin | A11 | Pimelic diphenylamide 106 |
| B2 | UNC0321 (trifluoroacetate salt) | B2 | (S)-HDAC-42 |
| B3 | (−)-Neplanocin A | B3 | MS-275 |
| B4 | Cl-Amidine | B4 | HNHA |
| B5 | F-Amidine (trifluoroacetate salt) | B5 | RG-108 |
| B6 | JGB1741 | B6 | 2′,3′,5′-triacetyl-5-azacytidine |
| B7 | UNC0638 | B7 | S-Adenosylhomocysteine |
| B8 | Phthalazinone pyrazole | B8 | UNC0224 |
| B9 | Isoliquiritigenin | B9 | Chidamide |
| B10 | CCG-100602 | B10 | 3-Deazaneplanocin A |
| B11 | CAY10669 | B11 | Sinefungin |
| C2 | Zebularine | C2 | Pyroxamide |
| C3 | Delphinidin chloride | C3 | WDR5-0103 |
| C4 | ITF 2357 | C4 | AMI-1 (sodium salt) |
| C5 | PFI-1 | C5 | UNC1215 |
| C6 | 5-Azacytidine | C6 | GSK 343 |
| C7 | Decitabine | C7 | SIRT1/2 inhibitor IV |
| C8 | (+)-JQ1 | C8 | I-CBP112 (hydrochloride) |
| C9 | (−)-JQ1 | C9 | UNC1999 |
| C10 | BSI-201 | C10 | PFI-3 |
| C11 | 1-Naphthoic acid | C11 | trans-Resveratrol |
| D2 | Sodium 4-phenylbutyrate | D2 | 2,4-DPD |
| D3 | IOX1 | D3 | DMOG |
| D4 | MI-2 (hydrochloride) | D4 | Trichostatin A |
| D5 | MI-nc (hydrochloride) | D5 | CAY10398 |
| D6 | Gemcitabine | D6 | RSC-133 |
| D7 | Lomeguatrib | D7 | KD 5170 |
| D8 | Octyl-α-ketoglutarate | D8 | CAY10433 |
| D9 | Daminozide | D9 | Piceatannol |
| D10 | GSK-J1 (sodium salt) | D10 | CAY10591 |
| D11 | GSK-J2 (sodium salt) | D11 | EX-527 |
| E2 | GSK-J4 (hydrochloride) | E2 | SAHA |
| E3 | GSK-J5 (hydrochloride) | E3 | 2-PCPA (hydrochloride) |
| E4 | CPTH2 | E4 | Nicotinamide |
| E5 | Valproic acid (sodium salt) | E5 | BIX01294 |
| E6 | Tenovin-1 | E6 | N-Oxalylglycine |
| E7 | Tenovin-6 | E7 | Suramin (sodium salt) |
| E8 | Sodium butyrate | ||
| E9 | Anacardic acid | ||
The identities of the chemicals and composition of the library, 94 chemicals distributed over two 96-well plates, are shown. The library (Cayman Chemical Item No. 11076, Batch No. 0455098) was received as 10 mM stocks of each chemical in DMSO