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. 2020 Oct 5;2020:6152356. doi: 10.1155/2020/6152356

Table 1.

Summary of the various changes that are observed in antibacterial-treated Salmonella cells with Gt2, Cys5-4, and Gt28 peptide extracts.

Peptide/concentration applied (MIC) Alteration Brief description
Gt2/1 X MIC Spheroplasts Spherical bacteria; changed shape, the inner and outer membranes were intact, but they lost of peptidoglycans.
Gt2/2 X MIC Spheroplasts Spherical bacteria; changed shape, the inner and outer membranes were intact, but they lost of peptidoglycans.
“Ghost's cells” The bacterial cells devoid or near-devoid of cytoplasm.
Filamentation Bacteria become much larger than normal.
Intracellular vacuolation Round-shaped transparent areas present in the bacterial cytoplasm.
Cys5-4/1 X MIC Spheroplasts Spherical bacteria; changed shape, the inner and outer membranes were intact, but they lost of peptidoglycans.
Cys5-4/2 X MIC Filamentation Bacteria become much larger than normal.
Intracellular vacuolation Round-shaped transparent areas present in the bacterial cytoplasm.
Gt28/1 X MIC Filamentation Bacteria become much larger than normal.
Cell envelope layer separation An increase in the distance between the cytoplasmic membrane and outer membrane of the gram-negative cell envelope.
“Ghost's cells” The bacterial cells devoid or near-devoid of cytoplasm.
Cell lysis The cell membrane was damaged leading to leakage.
Gt28/2 X MIC “Ghost's cells” The bacterial cells devoid or near-devoid of cytoplasm.
Cell envelope layer separation An increase in the distance between the cytoplasmic membrane and outer membrane of the gram-negative cell envelope.