Table 1.
Summary of the various changes that are observed in antibacterial-treated Salmonella cells with Gt2, Cys5-4, and Gt28 peptide extracts.
Peptide/concentration applied (MIC) | Alteration | Brief description |
---|---|---|
Gt2/1 X MIC | Spheroplasts | Spherical bacteria; changed shape, the inner and outer membranes were intact, but they lost of peptidoglycans. |
Gt2/2 X MIC | Spheroplasts | Spherical bacteria; changed shape, the inner and outer membranes were intact, but they lost of peptidoglycans. |
“Ghost's cells” | The bacterial cells devoid or near-devoid of cytoplasm. | |
Filamentation | Bacteria become much larger than normal. | |
Intracellular vacuolation | Round-shaped transparent areas present in the bacterial cytoplasm. | |
Cys5-4/1 X MIC | Spheroplasts | Spherical bacteria; changed shape, the inner and outer membranes were intact, but they lost of peptidoglycans. |
Cys5-4/2 X MIC | Filamentation | Bacteria become much larger than normal. |
Intracellular vacuolation | Round-shaped transparent areas present in the bacterial cytoplasm. | |
Gt28/1 X MIC | Filamentation | Bacteria become much larger than normal. |
Cell envelope layer separation | An increase in the distance between the cytoplasmic membrane and outer membrane of the gram-negative cell envelope. | |
“Ghost's cells” | The bacterial cells devoid or near-devoid of cytoplasm. | |
Cell lysis | The cell membrane was damaged leading to leakage. | |
Gt28/2 X MIC | “Ghost's cells” | The bacterial cells devoid or near-devoid of cytoplasm. |
Cell envelope layer separation | An increase in the distance between the cytoplasmic membrane and outer membrane of the gram-negative cell envelope. |