TABLE 3.
Variables | Univariate logistic regression analysis | Multivariate logistic regression analysis a | ||||
---|---|---|---|---|---|---|
OR | 95% CI | p Value | OR | 95% CI | p Value | |
Demographic characteristics | ||||||
Age | 1.035 | 1.003–1.065 | .022 | |||
Male | 0.879 | 0.531–1.454 | .615 | |||
Vascular risk factors | ||||||
Hypertension | 1.943 | 1.124–3.358 | .017 | 1.732 | 1.049–3.161 | .044 |
Hyperlipidemia | 0.977 | 0.531–1.859 | .943 | |||
Smoking | 3.071 | 1.694–5.567 | .001 | 2.568 | 1.360–4.849 | .005 |
Previous ischemic stroke | 1.577 | 1.760–3.269 | .021 | |||
Previous coronary heart disease | 1.103 | 0.508–2.397 | .604 | |||
Clinical data | ||||||
Antihypertensive medication | 1.183 | 0.699–2.002 | .531 | |||
Antidiabetic medication | 1.140 | 0.657–1.978 | .640 | |||
Antiplatelet medication | 1.042 | 0.556–1.951 | .898 | |||
Statin medication | 1.893 | 0.976–3.671 | .069 | |||
Systolic blood pressure | 1.066 | 0.992–1.022 | .393 | |||
Diastolic blood pressure | 1.003 | 0.981–1.026 | .774 | |||
Body mass index | 1.065 | 0.975–1.164 | .161 | |||
Laboratory data | ||||||
Total cholesterol | 1.050 | 0.797–1.383 | .730 | |||
Triglyceride | 1.328 | 1.008–2.063 | .048 | |||
Low‐density lipoprotein | 1.257 | 0.896–1.764 | .185 | |||
High‐density lipoprotein | 0.710 | 0.373–1.349 | .295 | |||
Hypersensitive C‐reactive protein | 1.018 | 0.956–1.085 | .573 | |||
Homocysteine | 1.080 | 1.028–1.136 | .002 | 1.061 | 1.006–1.118 | .028 |
Fasting blood glucose | 1.045 | 0.918–1.190 | .504 | |||
Hemoglobin A1c | 1.141 | 1.070–1.343 | .041 | 1.096 | 1.014–1.313 | .043 |
Glutathione peroxidase‐3 | ||||||
1st tertile | 2.124 | 1.130–3.992 | .019 | 1.870 | (1.124–3.669) | .024 |
2nd tertile | 1.784 | 0.995–3.332 | .069 | 1.615 | 0.802–3.252 | .179 |
3rd tertile | Reference | Reference | Reference | Reference |
Multivariable analysis was adjusted for age, hypertension, smoking, previous ischemic stroke, statin medication, triglyceride, homocysteine, and hemoglobin A1c levels.