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Randomized clinical trials ongoing on promising inflammatory strategy
| Target | Drug type | Drugs |
| IL 6 signaling | Anti-IL 6 | Clazakizumab, Siltuximab |
| Anti-IL6 receptor | Sarilumab, Tocilizumab | |
| IL 1 signaling | Anti-IL1β | Canakinumab |
| Anti-IL1 repector | Anakinra | |
| JAK-STAT signaling | JAK1/JAK2 inhibitors | Baricitinib, Ruxolitinib |
| JAK1/JAK3 inhibitors | Tofacitinib |
JAK-STAT: The Janus kinase/signal transducer and activator of tran-ions; IL: Interleukin.
