Table 1.
Ref. | Country | M/F ratio | Age, mean or median | Period of recruitment | PC cases/AP cases | AP verification | PC verification | Effect value and 95%CI |
Cohort studies | ||||||||
Rijkers et al[20], 2017 | Netherlands | 1.19 | 58.0 | 2004-2007 | 5/731 | Clinical evaluation | Clinical evaluation | SIR 1.1 (0.3-3.3) |
Kirkegård et al[21], 20181 | Denmark | 1.21 | 55.8 | 1980-2013 | 937/41669 | ICD code | ICD code | HR 2.02 (1.57-2.61)2 |
Pang et al[22], 20181 | China | 0.69 | 51.5 | 2004-2008 | 13/1066 | ICD code | ICD code | HR 9.99 (3.20-31.16)2 |
Munigala et al[23], 20141 | United States | 13.29 | 57.0 | 1998-2000 | 86/5720 | ICD code | ICD code | RR 1.05 (0.14-7.68)2 |
Chung et al[24], 20121 | China | 1.96 | > 40 | 2000-2003 | 11/747 | ICD code | ICD code | HR 9.10 (3.81-21.76) |
Ekbom et al[25], 1994 | Sweden | 1.19 | 55.6 | 1965-1983 | NA/NA | ICD code | ICD code | SIR 0.9 (0.2-2.5)2 |
Sadr-Azodi et al[10], 20181 | Sweden | 1.06 | 62.0 | 1997-2013 | 536/49749 | ICD code | ICD code | HR 1.24 (0.68-2.25)2 |
Goldacre et al[26], 20081 | Britain | 0.88 | NA | 1963-1999 | 91/24993 | ICD code | ICD code | RR 5.70 (4.54-7.08) |
Karlson et al[14], 19971 | Sweden | 1.49 | 54.5 | 1965-1983 | 152/24753 | ICD code | ICD code | SIR 1.6 (1.3-2.0)2 |
Case-control studies | ||||||||
Bansal et al[27], 19951 | United States | NA | 57.0 | 1988-1992 | 2639/64 | ICD code | ICD code | OR 1.76 (1.28-2.41) |
Duell et al[13], 20061 | United States | NA | > 21 | 1995-1999 | 308/16 | Self-reported (physician diagnosed) | Pathology+ physician reported | OR 6.4 (2.7-15) |
Effect values in the study have matched/adjustment variables.
Effect values are extracted from included studies according to the longest follow-up time. AP: Acute pancreatitis; CI: Confidence interval; F: Female; HR: Hazard ratio; ICD: International Classification of Diseases; M: Male; OR: Odds ratio; PC: Pancreatic cancer; RR: Relative risk; SIR: Standardized incidence ratio.