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. 2020 Oct 1;11:571319. doi: 10.3389/fimmu.2020.571319

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Copyright © 2020 Yegorov, Babenko, Kozhakhmetov, Akhmaltdinova, Kadyrova, Nurgozhina, Nurgaziyev, Good, Hortelano, Yermekbayeva and Kushugulova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences in the levels of analytes representative of major functional groups of immune response mediators in the gut of individuals with (“Ps”) and without psoriasis (controls, “C”). (A) IL-1α (Proinflammatory); (B) IL-4 (Th1/Th2); (C) Il-7 (Homeostatic); (D) IL-9 (Th9); (E) IL-10 (Anti-inflammatory); (F) IL-15 (Growth factor); (G) IFN-α2 (Interferons); (H) GM-CSF (Colony-stimulating factor); (I) MIP-1β (Chemokine). For all depicted analytes data were available for 23/40 (psoriasis+, N = 13, and psoriasis-, N = 10) participants. Statistical significance assessed by the Independent-Samples Mann-Whitney U test. Source data are provided as a Supplementary Material.