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. 2020 Oct 1;11:571319. doi: 10.3389/fimmu.2020.571319

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Copyright © 2020 Yegorov, Babenko, Kozhakhmetov, Akhmaltdinova, Kadyrova, Nurgozhina, Nurgaziyev, Good, Hortelano, Yermekbayeva and Kushugulova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Microbial species α-diversity measured by Shannon index in the gut of the psoriasis individuals and controls. (B) Gut Firmicutes/Bacteroides ratio of psoriasis + individuals and controls. (C) Heatmap showing the LefSe-derived LDA scores for each of the OTU (n = 18) differentially abundant in the gut of psoriasis + participants. Data based on N = 21 samples. (D) Heatmap based on the Pearson coefficients of correlation between the psoriasis-associated microbial taxa, baseline IL-1α and PASI scores. Analysis based on N = 14 samples. Significant correlations marked by asterisks (*).