Table 1.
Parameters for the lung function test (Figure 2): data are presented as mean ± SD.
| Parameters | WT (Wildtype) | Pallid Mice | Empty Vector | hAAT Plasmid |
|---|---|---|---|---|
| Static Compliance (mL/cmH2O) | 0.068 ± 0.004 | 0.0767 ± 0.004 | 0.0749 ± 0.001 | 0.064 ± 0.002 |
| Total Lung capacity (A) (mL) | 0.80 ± 0.04 | 0.95 ± 0.03 | 0.99 ± 0.06 | 0.73 ± 0.01 |
| Hysteresis (cmH2O/mL) | 3.29 ± 0.34 | 4.70 ± 0.31 | 5.50 ± 0.13 | 3.66 ± 0.40 |
| AUC (area under curve) (mL/cmH2O) | 0.39 ± 0.06 | 0.72 ± 0.10 | 0.73 ± 0.11 | 0.47 ± 0.06 |
| k (curvature of the upper portion of the deflation limb of the pressure volume (PV) curve) | 0.11 ± 0.006 | 0.13 ± 0.004 | 0.143 ± 0.0005 | 0.12 ± 0.004 |