Table 4.

Inhibitory effects of various pesticides to hOCT1- and hOCT2-mediated ³H-MPP uptake and MATE1-mediated ¹⁴C-metformin uptake.

Pesticides (9)	Inhibitory Effects (%)
	OCT1		OCT2		MATE1
	10 µM	100 µM	10 µM	100 µM	10 µM	100 µM
Imazalil	56	84	39	61	33	83
Propamocarb	9	49	24	54	22	25
Azoxystrobin	17	44	33	38	27	68
Prochloraz	14	42	32	33	7	70
Atrazin	−8	15	1	10	18	32
Amitraz	8	12	9	27	−11	12
Glyphosat	1	7	12	2	−1	14
Imidacloprid	4	1	−3	19	−8	29
Paraquat *	0	−1	−6	−4	3	4

* The asterisk shows the compound which is already published to interact with hOCT1 but not with all rodent Oct1 [21].