Table 2.
Men | Women | Overall | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Obs 1 | Exp 2 | SMR 3 | 95% CI 4 | Obs | Exp | SMR | 95% CI | Obs | Exp | SMR | 95% CI | ||||
Overall | 11,829 | 9512.57 | 1.24 | 1.22 | 1.27 | 18,371 | 12,849.93 | 1.43 | 1.41 | 1.45 | 30,200 | 22,362.50 | 1.35 | 1.34 | 1.37 |
Age at diagnosis | |||||||||||||||
40–49 | 1216 | 823.09 | 1.48 | 1.40 | 1.56 | 643 | 284.53 | 2.26 | 2.09 | 2.44 | 1859 | 1107.62 | 1.68 | 1.60 | 1.76 |
50–59 | 3026 | 2416.27 | 1.25 | 1.21 | 1.30 | 2643 | 1456.06 | 1.82 | 1.75 | 1.89 | 5669 | 3872.33 | 1.46 | 1.43 | 1.50 |
60–69 | 4267 | 3452.83 | 1.24 | 1.20 | 1.27 | 6339 | 4070.97 | 1.56 | 1.52 | 1.60 | 10,606 | 7523.81 | 1.41 | 1.38 | 1.44 |
≥70 | 3320 | 2820.37 | 1.18 | 1.14 | 1.22 | 8746 | 7038.38 | 1.24 | 1.22 | 1.27 | 12,066 | 9858.75 | 1.22 | 1.20 | 1.25 |
p < 0.001 | p < 0.001 | p < 0.001 | |||||||||||||
Age at death | |||||||||||||||
40–49 | 116 | 6.12 | 18.97 | 15.81 | 22.75 | 38 | 0.87 | 43.64 | 31.76 | 59.98 | 154 | 6.99 | 22.04 | 18.82 | 25.81 |
50–59 | 1112 | 431.17 | 2.58 | 2.43 | 2.74 | 554 | 116.75 | 4.75 | 4.37 | 5.16 | 1666 | 547.93 | 3.04 | 2.90 | 3.19 |
60–69 | 2858 | 1873.01 | 1.53 | 1.47 | 1.58 | 2197 | 823.51 | 2.67 | 2.56 | 2.78 | 5055 | 2696.52 | 1.87 | 1.82 | 1.93 |
≥70 | 7743 | 7202.27 | 1.08 | 1.05 | 1.10 | 15,582 | 11,908.79 | 1.31 | 1.29 | 1.33 | 23,325 | 19,111.07 | 1.22 | 1.20 | 1.24 |
p < 0.001 | p < 0.001 | p < 0.001 | |||||||||||||
Time after diagnosis * | |||||||||||||||
1–5 | 1506 | 1445.09 | 1.04 | 0.99 | 1.10 | 1748 | 1530.28 | 1.14 | 1.09 | 1.20 | 3254 | 2975.37 | 1.09 | 1.06 | 1.13 |
6–10 | 4321 | 3734.52 | 1.16 | 1.12 | 1.19 | 5945 | 4611.66 | 1.29 | 1.26 | 1.32 | 10,266 | 8346.18 | 1.23 | 1.21 | 1.25 |
>10 | 3025 | 2361.79 | 1.28 | 1.24 | 1.33 | 4886 | 3455.61 | 1.41 | 1.37 | 1.45 | 7911 | 5817.40 | 1.36 | 1.33 | 1.39 |
p < 0.001 | p < 0.001 | p < 0.001 | |||||||||||||
Glucose-lowering drugs | |||||||||||||||
Oral | 9329 | 8252.28 | 1.13 | 1.11 | 1.15 | 14,764 | 11,305.37 | 1.31 | 1.29 | 1.33 | 24,093 | 19,557.64 | 1.23 | 1.22 | 1.25 |
Insulin and oral | 1650 | 872.50 | 1.89 | 1.80 | 1.98 | 2624 | 1178.46 | 2.23 | 2.14 | 2.31 | 4274 | 2050.96 | 2.08 | 2.02 | 2.15 |
Insulin | 850 | 387.79 | 2.19 | 2.05 | 2.34 | 983 | 366.10 | 2.69 | 2.52 | 2.86 | 1833 | 753.89 | 2.43 | 2.32 | 2.55 |
1 Obs, observed; 2 Exp, expected; 3 SMR, standardized mortality ratio; 4 CI, confidence interval; * prevalent diabetes cases at beginning of follow-up excluded from analysis.