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. 2020 Sep 20;17(18):6870. doi: 10.3390/ijerph17186870

Table 2.

Standardized mortality ratios for all causes of death for men, women, and the overall cohort according to sex, age at diagnosis, age at death, time after diagnosis, and therapy.

Men Women Overall
Obs 1 Exp 2 SMR 3 95% CI 4 Obs Exp SMR 95% CI Obs Exp SMR 95% CI
Overall 11,829 9512.57 1.24 1.22 1.27 18,371 12,849.93 1.43 1.41 1.45 30,200 22,362.50 1.35 1.34 1.37
Age at diagnosis
40–49 1216 823.09 1.48 1.40 1.56 643 284.53 2.26 2.09 2.44 1859 1107.62 1.68 1.60 1.76
50–59 3026 2416.27 1.25 1.21 1.30 2643 1456.06 1.82 1.75 1.89 5669 3872.33 1.46 1.43 1.50
60–69 4267 3452.83 1.24 1.20 1.27 6339 4070.97 1.56 1.52 1.60 10,606 7523.81 1.41 1.38 1.44
≥70 3320 2820.37 1.18 1.14 1.22 8746 7038.38 1.24 1.22 1.27 12,066 9858.75 1.22 1.20 1.25
p < 0.001 p < 0.001 p < 0.001
Age at death
40–49 116 6.12 18.97 15.81 22.75 38 0.87 43.64 31.76 59.98 154 6.99 22.04 18.82 25.81
50–59 1112 431.17 2.58 2.43 2.74 554 116.75 4.75 4.37 5.16 1666 547.93 3.04 2.90 3.19
60–69 2858 1873.01 1.53 1.47 1.58 2197 823.51 2.67 2.56 2.78 5055 2696.52 1.87 1.82 1.93
≥70 7743 7202.27 1.08 1.05 1.10 15,582 11,908.79 1.31 1.29 1.33 23,325 19,111.07 1.22 1.20 1.24
p < 0.001 p < 0.001 p < 0.001
Time after diagnosis *
1–5 1506 1445.09 1.04 0.99 1.10 1748 1530.28 1.14 1.09 1.20 3254 2975.37 1.09 1.06 1.13
6–10 4321 3734.52 1.16 1.12 1.19 5945 4611.66 1.29 1.26 1.32 10,266 8346.18 1.23 1.21 1.25
>10 3025 2361.79 1.28 1.24 1.33 4886 3455.61 1.41 1.37 1.45 7911 5817.40 1.36 1.33 1.39
p < 0.001 p < 0.001 p < 0.001
Glucose-lowering drugs
Oral 9329 8252.28 1.13 1.11 1.15 14,764 11,305.37 1.31 1.29 1.33 24,093 19,557.64 1.23 1.22 1.25
Insulin and oral 1650 872.50 1.89 1.80 1.98 2624 1178.46 2.23 2.14 2.31 4274 2050.96 2.08 2.02 2.15
Insulin 850 387.79 2.19 2.05 2.34 983 366.10 2.69 2.52 2.86 1833 753.89 2.43 2.32 2.55

1 Obs, observed; 2 Exp, expected; 3 SMR, standardized mortality ratio; 4 CI, confidence interval; * prevalent diabetes cases at beginning of follow-up excluded from analysis.