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. 2020 Sep 11;17(18):6626. doi: 10.3390/ijerph17186626

Table 3.

Predicted logKow and logt1/2 values of quinolone derivatives using QSAR models.

No. logKow Relative Error (%) logt1/2 Relative Error (%)
Trovafloxacin 2.436 2.267
Derivative-1 0.940 −61.41% 1.801 −20.56%
Derivative-2 1.537 −36.90% 1.994 −12.04%
Derivative-3 1.226 −49.67% 1.819 −19.76%
Derivative-4 1.319 −45.85% 2.001 −11.73%
Derivative-5 1.173 −51.85% 1.988 −12.31%
Derivative-6 0.991 −59.32% 1.806 −20.34%
Derivative-7 1.490 −38.83% 2.031 −10.41%
Derivative-8 1.412 −42.04% 2.062 −9.04%
Derivative-9 1.396 −42.69% 2.006 −11.51%
Derivative-10 1.166 −52.13% 2.023 −10.76%
Derivative-11 1.182 −51.48% 2.032 −10.37%