Table 1.
In vitro anti-TB activity of compound 1 and its Schiff bases 2, 3, and 4 against H37Rv and MDR strains of MTB.
| Compound Code a | MIC (µg/mL) | |
|---|---|---|
| H37Rv | MDR-MTB b | |
| 1 | 5.5 | 11 |
| 2 | 20 | NA |
| 3 | 11 | NA |
| 4 | 20 | NA |
Note: MIC, minimum inhibitory concentration. a The synthesis and characterization of test compounds 1–4 are detailed in our previous reports [56,57]. b These isolates were resistant to rifampicin (1 µg/mL) and isoniazid (0.2 µg/mL). NA, not active (the concentration considered for screening was 0.2–32 µg/mL).