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. 2020 Oct 2;20:101221. doi: 10.1016/j.pmedr.2020.101221

Table 2.

Hazard ratio (HR)a of dementia between categories of potential risk factors in the Finnish Mobile Clinic Follow-up Survey.

Variable Category Number of dementia Number at risk HR 95%CI
Demographic variables
Sex Male 707 7023 1
Female 1064 6740 0.87 0.77–0.98
Age, years 30–39 118 3830 1
40–49 536 3938 5.84 4.77–7.15
50–59 682 3400 16.6 13.5–20.4
60–69 435 2595 55.3 44.0–69.5
Education Basic 1358 9703 1
Intermediate 313 3187 0.82 0.72–0.93
Higher 100 873 0.83 0.67–1.02
Marital status Unmarried 180 1605 1
Married 1359 10,720 0.96 0.82–1.13
Widow 177 959 0.87 0.70–1.08
Divorced 55 479 0.85 0.63–1.16
Region type Urban 758 5633 1
Rural 639 4971 0.87 0.78–0.97
Industrial 374 3159 0.85 0.75–0.97
Lifestyle
Leisure time physical activity Inactive 459 3527 1
Occasionally 1125 8691 0.99 0.89–1.11
Regularly 187 1645 0.98 0.82–1.17
Smoking Never 1140 7448 1
Former 312 2624 0.97 0.83–1.12
Current 319 3691 1.25 1.08–1.44
Alcohol None 1016 6189 1
consumptionb Moderate 698 6876 0.83 0.74–0.93
Heavy 57 698 1.00 0.76–1.33
Metabolic health
Body mass index <25 701 6287 1
(kg/m2) 25–29.9 769 5513 0.97 0.87–1.08
≥30 301 1963 1.08 0.94–1.25
Blood pressurec Normal 555 5253 1
Elevated 1216 8510 1.08 0.97–1.21
Plasma fast. glucosed <5.6 1093 8905 1
(mmol/l) ≥5.6 678 4858 1.15 1.05–1.28
Serum triglyceridesd <1.7 1318 10,334 1
(mmol/l) ≥1.7 453 3429 1.12 1.00–1.25
Serum cholesterol <6 333 3305 1
(mmol/l) ≥6 1438 10,458 0.96 0.85–1.08

Diabetes Federation (Alberti et al., 2006).

a

The model included all variables in the table and the number at risk (N = 13763) included all individuals with no missing data in any of the variables in the model.

b

Total alcohol consumption: None = 0; Moderate = 1–199 g/week for men and 1–99 g/week for women; Heavy ≥ 200 g/week for men and ≥ 100 g/week for women.

c

Blood pressure was considered elevated if systolic pressure was ≥ 140 or diastolic pressure ≥ 90 or antihypertensive medication was used.

d

The cut-off was based on the definition of metabolic syndrome, according to the International