Table 2.
Variable | Category | Number of dementia | Number at risk | HR | 95%CI |
---|---|---|---|---|---|
Demographic variables | |||||
Sex | Male | 707 | 7023 | 1 | |
Female | 1064 | 6740 | 0.87 | 0.77–0.98 | |
Age, years | 30–39 | 118 | 3830 | 1 | |
40–49 | 536 | 3938 | 5.84 | 4.77–7.15 | |
50–59 | 682 | 3400 | 16.6 | 13.5–20.4 | |
60–69 | 435 | 2595 | 55.3 | 44.0–69.5 | |
Education | Basic | 1358 | 9703 | 1 | |
Intermediate | 313 | 3187 | 0.82 | 0.72–0.93 | |
Higher | 100 | 873 | 0.83 | 0.67–1.02 | |
Marital status | Unmarried | 180 | 1605 | 1 | |
Married | 1359 | 10,720 | 0.96 | 0.82–1.13 | |
Widow | 177 | 959 | 0.87 | 0.70–1.08 | |
Divorced | 55 | 479 | 0.85 | 0.63–1.16 | |
Region type | Urban | 758 | 5633 | 1 | |
Rural | 639 | 4971 | 0.87 | 0.78–0.97 | |
Industrial | 374 | 3159 | 0.85 | 0.75–0.97 | |
Lifestyle | |||||
Leisure time physical activity | Inactive | 459 | 3527 | 1 | |
Occasionally | 1125 | 8691 | 0.99 | 0.89–1.11 | |
Regularly | 187 | 1645 | 0.98 | 0.82–1.17 | |
Smoking | Never | 1140 | 7448 | 1 | |
Former | 312 | 2624 | 0.97 | 0.83–1.12 | |
Current | 319 | 3691 | 1.25 | 1.08–1.44 | |
Alcohol | None | 1016 | 6189 | 1 | |
consumptionb | Moderate | 698 | 6876 | 0.83 | 0.74–0.93 |
Heavy | 57 | 698 | 1.00 | 0.76–1.33 | |
Metabolic health | |||||
Body mass index | <25 | 701 | 6287 | 1 | |
(kg/m2) | 25–29.9 | 769 | 5513 | 0.97 | 0.87–1.08 |
≥30 | 301 | 1963 | 1.08 | 0.94–1.25 | |
Blood pressurec | Normal | 555 | 5253 | 1 | |
Elevated | 1216 | 8510 | 1.08 | 0.97–1.21 | |
Plasma fast. glucosed | <5.6 | 1093 | 8905 | 1 | |
(mmol/l) | ≥5.6 | 678 | 4858 | 1.15 | 1.05–1.28 |
Serum triglyceridesd | <1.7 | 1318 | 10,334 | 1 | |
(mmol/l) | ≥1.7 | 453 | 3429 | 1.12 | 1.00–1.25 |
Serum cholesterol | <6 | 333 | 3305 | 1 | |
(mmol/l) | ≥6 | 1438 | 10,458 | 0.96 | 0.85–1.08 |
Diabetes Federation (Alberti et al., 2006).
The model included all variables in the table and the number at risk (N = 13763) included all individuals with no missing data in any of the variables in the model.
Total alcohol consumption: None = 0; Moderate = 1–199 g/week for men and 1–99 g/week for women; Heavy ≥ 200 g/week for men and ≥ 100 g/week for women.
Blood pressure was considered elevated if systolic pressure was ≥ 140 or diastolic pressure ≥ 90 or antihypertensive medication was used.
The cut-off was based on the definition of metabolic syndrome, according to the International