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. 2020 Aug 27;12(9):811. doi: 10.3390/pharmaceutics12090811

Figure 5.

Figure 5

In Vitro release of TQ NPs conducted in phosphate buffered saline (PBS) (pH 7.4) and acetate buffer (pH 5.0). Results are presented as mean ± SD of cumulative % amount of TQ released from (A) F1-NC and (B) F2-NC up to 48 h. The PCL MW impacted the release kinetics. F1-NC with a shorter PCL chain achieved 86–90% cumulative release within the first 8 h in neutral and acidic media, respectively. Conversely, TQ release from F2-NC with the longer PCL chain was more sustained at pH 7.4, reaching 76% cumulative release within the first 8 h and 86% release after 24 h, which was accelerated in acidic media to 94 and 99% at 8 and 24 h, respectively.